报告题目：Relation between blood pressure and pulse wave velocity forhuman arteries
报告人：Prof. Yonggang Huang
Continuous monitoring of blood pressure, an essential measure of health status, typically requires complex, costly and invasive techniques that can expose patients to risks of complications. Continuous, cuffless, and noninvasive blood pressure monitoring methods that correlate measured pulse wave velocity (PWV) to the blood pressure via the Moens−Korteweg (MK) and Hughes Equations, offer promising alternatives. The MK Equation, however, involves two assumptions that do not hold for human arteries, and the Hughes Equation is empirical, without any theoretical basis. The results presented here establish a relation between the blood pressure P and PWV that does not rely on the Hughes Equation nor on the assumptions used in the MK Equation. This relation degenerates to the MK Equation under extremely low blood pressures, and it accurately captures the results of in vitro experiments using artificial blood vessels at comparatively high pressures. For human arteries, which are well characterized by the Fung hyperelastic model, a simple formula between P and PWV is established within the range of human blood pressures. This formula is validated by literature data as well as by experiments on human subjects, with applicability in the determination of blood pressure from PWV in continuous, cuffless, and noninvasive blood pressure monitoring systems.
黄永刚教授曾任美国工程科学协会主席，现任美国机械工程师协会应用力学执行委员会主席，力学领域顶尖期刊Journal of Applied Mechanics主编，中国力学学会Theoreticaland Applied Mechanics Letter共同主编，NPG Flexible Electronics 副主编。至今发表SCI论文500余篇,包括《科学》10篇、《自然》5篇、《细胞》1篇等顶级期刊。